Curated luxury hotels in Appalachian Mountains

When you stay at The Siena Hotel, Autograph Collection in Chapel Hill, you'll be in the suburbs, within a 15-minute drive of Duke University and University of North Carolina. This boutique hotel is 8 mi (12.9 km) from Streets at Southpoint Mall and 8.8 mi (14.2 km) from Duke University Hospital.

Located in Lexington, Marriott Lexington Griffin Gate Golf Resort & Spa is in the suburbs, within a 10-minute drive of Transylvania University and Applebee s Park. This golf resort is 3.5 mi (5.6 km) from Legends Field and 3.6 mi (5.7 km) from Hunt-Morgan House.

With a stay at AC Hotel by Marriott Charlotte SouthPark in Charlotte (SouthPark), you'll be a 1-minute drive from SouthPark Mall and 9 minutes from Spectrum Center. This hotel is 6 mi (9.7 km) from Charlotte Convention Center and 6.1 mi (9.9 km) from Bank of America Stadium.

With a stay at 21c Museum Hotel Lexington, you'll be centrally located in Lexington, within a 5-minute drive of University of Kentucky and Red Mile Racetrack. This hotel is 8.3 mi (13.4 km) from Kentucky Horse Park and 3.4 mi (5.4 km) from Hamburg Place.

When you stay at JB Duke Hotel in Durham, you'll be near the airport, just steps from Duke University and 9 minutes by foot from Cameron Indoor Stadium. This hotel is 1.4 mi (2.3 km) from Duke University Hospital and 1.5 mi (2.4 km) from Duke University Chapel.

When you stay at Dollywood's DreamMore Resort in Pigeon Forge, you'll be in a national park – a 3-minute drive from Dollywood's Splash Country and 6 minutes from LeConte Center at Pigeon Forge. This family-friendly resort is 2.6 mi (4.3 km) from Dollywood and 3.1 mi (5 km) from Island at Pigeon Forge.

DoubleTree by Hilton Asheville Downtown is in the heart of Asheville, within a 5-minute walk of Harrah's Cherokee Center - Asheville and Grove Arcade. This hotel is 0.4 mi (0.6 km) from Downtown Market Asheville and 0.5 mi (0.8 km) from Altamont Theater.

A stay at 21c Museum Hotel Durham places you in the heart of Durham, within a 5-minute walk of Carolina Theatre and Durham Performing Arts Center. This hotel is 0.2 mi (0.4 km) from Durham Convention Center and 0.3 mi (0.4 km) from American Tobacco Campus.

With a stay at The Windsor Boutique Hotel, you'll be centrally located in Asheville, steps from Diana Wortham Theatre and Thomas Wolfe Memorial. This boutique hotel is 0.4 mi (0.6 km) from Harrah's Cherokee Center - Asheville and 0.4 mi (0.6 km) from The Orange Peel.

The Atterbury Hotel, Autograph Collection is centrally located in Pittsburgh – a 5-minute walk from PNC Park and 7 minutes by foot from David L Lawrence Convention Center. This historic hotel is 0.8 mi (1.3 km) from PPG Paints Arena and 1 mi (1.6 km) from Acrisure Stadium.

With a stay at The Durham Hotel, you'll be centrally located in Durham, steps from Carolina Theatre and within a 10-minute walk of Durham Performing Arts Center. This boutique hotel is 0.5 mi (0.7 km) from Durham Bulls Athletic Park and 0.8 mi (1.3 km) from Duke University.

With a stay at Grandover Resort & Spa, a Wyndham Grand Hotel in Greensboro (Sedgefield), you'll be within a 15-minute drive of First Horizon Coliseum and Wet 'n Wild Emerald Pointe Water Park. This golf resort is 8.2 mi (13.1 km) from High Point University and 8.3 mi (13.3 km) from University of North Carolina at Greensboro.

When you stay at Sheraton Reston Hotel in Reston, you'll be next to a golf course, within a 15-minute drive of Tysons Corner Center and Reston Town Center. This golf hotel is 7.2 mi (11.6 km) from Steven F. Udvar-Hazy Center and 7.4 mi (11.8 km) from Fair Oaks Mall.

A stay at The Industrialist Hotel, Pittsburgh, Autograph Collection places you in the heart of Pittsburgh, within a 15-minute walk of PNC Park and PPG Paints Arena. This hotel is 0.5 mi (0.8 km) from David L Lawrence Convention Center and 0.6 mi (1 km) from Station Square.

With a stay at Margaritaville Resort Gatlinburg in Gatlinburg (Downtown Gatlinburg), you'll be steps from Ripley's Aquarium of the Smokies and 3 minutes by foot from Anakeesta. This spa hotel is 0.5 mi (0.9 km) from Gatlinburg SkyPark and 0.6 mi (1 km) from Gatlinburg Space Needle.

In the heart of Newark, DoubleTree by Hilton Hotel Newark Ohio is within a 5-minute drive of The Works Museum and Newark Earthworks. This hotel is 2.6 mi (4.3 km) from Ohio State University at Newark and 5.4 mi (8.7 km) from Dawes Arboretum.

With a stay at The Bristol Hotel, you'll be centrally located in Bristol, within a 15-minute drive of Bristol Motor Speedway and Cumberland Square Park. This hotel is 0.2 mi (0.3 km) from Paramount Center for the Arts and 0.2 mi (0.3 km) from Birthplace of Country Music Museum.

The Wayback, Pigeon Forge, A Tribute Portfolio Hotel is centrally located in Pigeon Forge – a 5-minute walk from Island at Pigeon Forge and a 3-minute drive from Titanic Museum. This hotel is 5.2 mi (8.3 km) from Dollywood and 7.2 mi (11.6 km) from Wilderness at the Smokies.

With a stay at Omni Charlotte Hotel, you'll be centrally located in Charlotte, steps from Queen City Quarter and Blumenthal Performing Arts Center. This hotel is 0.2 mi (0.3 km) from Mint Museum of Craft Design and 0.3 mi (0.5 km) from Discovery Place.

Located in Boyce, L'Auberge Provencale Inn & Restaurant is within a 5-minute drive of White Post Village Park and Virginia River Trips. This hotel is 14.7 mi (23.6 km) from Shenandoah National Park and 1.3 mi (2.1 km) from White Post Historic District.